Review and expert evaluation of the materials of the European meeting on hypersensitivity to drugs (DHM 2022)

The review article discusses the current data on mechanisms of hypersensitivity drugs reactions (HDRs). relevance problem is associated with a significant prevalence adverse drug reactions, in structure which immune allergic occupy proportion. Adverse according to literature, occur 10-20% hospitalized patients and about 25% outpatients. A serious HDRs their overdiagnosis, affects results individual treatment can have consequences case misdiagnosis, because it causes appropriate restrictions use necessary drugs. Purpose - analyze views recommendations allergy; highlight issues 2022 meeting, highlighted problems hypersensitivity. In particular, show relationship between viral infections severe skin such as lesion syndrome eosinophilia systemic disorders. reviews proposes algorithms that be used prevent development complications caused by HDRs. materials are based European Meeting organized Association Allergists Immunologists Verona, Italy. conclusions noted despite interest health care system large number studies publications allergy, today there an urgent need for accurate diagnostic approaches will ensure correct identification suspected combination tests determine cause possibility prescribing treatment. new mechanisms, phenotypes endotypes responses discussed future keys preventing further exposure harmful Preliminary pharmacogenomic screening (identification specific human leukocyte antigen genotypes reactions) certain groups before high-risk may become Ukraine. No conflict interests was declared author.